TABLE 2.
A Comparison of Effects of Neonatal EE and DES Exposure on the BW, the Paired Relative Weight (100 g BW) of the Testis, SV, HB/EP, T/EP, and EP Fat, and the Relative Weight of the BS, LA, and Penis in Adolescent and Adult Rats
| Group | BW (g) | Testis (g) | SV (g) | HB/EP (g) | T/EP (g) | EP Fat (g) | BS (g) | LA (g) | Penis (g) |
| Adolescent | |||||||||
| Control | 217 ± 11 | 1.1475 ±0.0251a | 0.1376 ± 0.0151a | 0.0975 ± 0.0039 | 0.0479 ± 0.0021a | 0.0227 ± 0.0007a | 0.1351 ± 0.0038a | 0.0421 ± 0.0018 | 0.0740 ± 0.0035a |
| DES, 100 ng | 228 ± 8 | 0.9279 ± 0.0331c | 0.0519 ± 0.0038b | 0.0851 ±0.0033 | 0.0363 ± 0.0011c | 0.0141 ± 0.0009b | 0.0804 ± 0.0056b | 0.0376 ± 0.0080 | 0.0453 ± 0.0032b |
| EE, 100 ng | 222 ± 4 | 1.0248 ± 0.0215b | 0.0637 ± 0.0054b | 0.0877 ± 0.0042 | 0.0430 ± 0.0013b | 0.0118 ± 0.0010b | 0.0819 ± 0.0062b | 0.0381 ± 0.0029 | 0.0469 ± 0.0027b |
| Adult | |||||||||
| Control | 456 ± 16 | 0.8789 ± 0.0241A | 0.3304 ± 0.0101A | 0.1579 ± 0.0031A | 0.1041 ± 0.0014A | 0.0700 ± 0.0050A | 0.1856 ± 0.0048A | 0.0551 ± 0.0013 | 0.0569 ± 0.0018A |
| DES, 100 ng | 481 ± 9 | 0.7428 ± 0.0197B | 0.2234 ± 0.0176B | 0.1376 ± 0.0029B | 0.0955 ± 0.0022B | 0.0321 ± 0.0028B | 0.1372 ± 0.0069B | 0.0538 ± 0.0025 | 0.0381 ± 0.0023B |
| EES, 100 ng | 493 ± 20 | 0.7272 ± 0.0177B | 0.2181 ± 0.0318B | 0.1317 ± 0.0040B | 0.0913 ± 0.0024B | 0.0360 ± 0.0023B | 0.1261 ± 0.0164B | 0.0470 ± 0.0030 | 0.0396 ± 0.0022B |
Note. BW, body weight; BS, bulbospongious; LA, levator ani; SV, seminal vesicle; HB/EP, head and body of the epididymis; T/EP, tail of the epididymis; EP fat, epididymal fat pad. Data are expressed as mean ±SEM. Means in the group “Adolescent” within columns with different superscripts (A–C) are significantly different (p < 0.05). Means in the group ADULT within columns with different superscripts (a and b) are significantly different (p < 0.05).