TABLE 3.
Fertility Data of Female Rats Cohabited with Males Treated Neonatally with Various Concentrations (10 ng–10 μg) of EE on Alternate Days from Postnatal Days 1 to 11 (Dose-Response Study) and of Female Rats Cohabited with Males Treated Neonatally with EE or DES at a Dose of 100 ng Daily for Postnatal Days 1–6 (Comparative Study)
| Group | Pregnant/mated | Plug positive/mated | Sperm positive/mated |
| Dose-response | |||
| ControlA | 5/5 | 5/5 | 5/5 |
| EE 10 ngA | 5/5 | 5/5 | 5/5 |
| EE 100 ngA,B | 3/5 | 3/5 | 3/5 |
| EE 1 μgB | 0/4 | 0/4 | 0/4 |
| EE 10 μgB | 0/5 | 0/5 | 0/5 |
| Comparative | |||
| ControlA | 5/6 | 6/6 | 6/6 |
| EE 100 ngB | 1/6 | 1/6 | 1/6 |
| DES 100 ngB | 0/6 | 1/6 | 1/6 |
Note. Columns with different superscripts (A and B) are significantly different (p < 0.05).