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. 2009 Oct 7;112(2):394–404. doi: 10.1093/toxsci/kfp220

FIG. 5.

FIG. 5.

The DOPAC/DA ratio is selectively altered in juvenile mice following exposure to manganese. The ratio of DOPAC/DA was decreased in juvenile mice (days 20–34) exposed to 30 mg/kg MnCl2 (A) but no changes were detected in either naive adult mice exposed to 10 or 30 mg/kg MnCl2 (B) or in adult mice preexposed to 10 or 30 mg/kg MnCl2 as juveniles (C). Differing letters denote statistical significance (p < 0.05).