TABLE 2.

Iron in Brain and Serum of Juvenile and Adult Mice Exposed to Manganese (parts per million)

Time of exposure	Treatment, mg/kg (MnCl2·4H2O)	Striatum	SN	Cortex	Hypothalamus	Serum
Juvenile	0	6.7 ± 1.4	10.1 ± 2.02	14.8 ± 9.6	17.2 ± 10.4	2.53 ± 0.32
	10	8.05 ± 1.9	18.3 ± 12.8a	10.7 ± 8.5	23.04 ± 8.87	3.32 ± 1.29
	30	9.3 ± 1.1	37.7 ± 1.23a	32.1 ± 1.23a	71.64 ± 90.6	4.79 ± 0.23
Adults	0	26.7 ± 2.23	14.9 ± 6.3	13.1 ± 4.7	19.8 ± 10.1	3.15 ± 0.27
	10	34.6 ± 1.32	41.2 ± 10.5	50.4 ± 14.1	28.7 ± 5.9	6.23 ± 0.62
	30	33.2 ± 1.57	43 ± 24	44.2 ± 3.35	41 ± 3.4a	5.13 ± 0.35
Juvenile and adult	0	26.6 ± 1.9	32.5 ± 0.35	23.3 ± 2.6	25.4 ± 2.28	2.91 ± 0.27
	10	35.4 ± 1.2	34.5 ± 1.83	34.3 ± 1.18	31.0 ± 1.24	3.4 ± 0.20
	30	34.7 ± 0.43	24.9 ± 2.5	24.3 ± 2.6	20.9 ± 1.86	6.2 ± 0.56

Note. Data shown are means ± SEM (n ≥ 3).

^aSignificance compared to controls within a specific brain region per exposure group is denoted by (p < 0.05).