Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mutational analysis of CLIC4 translocation. (A and B) Mutation of residue Cys35 (YFP-CLIC4(C35A)) abolishes LPA-induced translocation (A) and colocalization with DsRed-NHERF2 (B). Bars, 10 μm. (C) Structural comparison of omega-GST (GSTO1) and CLIC4. The indicated residues were mutated, based on their equivalence to the residues that mediate the binding of glutathione and secondary substrates in GSTs. Results are summarized in D. See text for details.
