Figure 8.

Comparison of DDMs and wire superpositions in a sequence of rigid-body transformations for tweezers functional motion of aspartate aminotransferase (9aat–1ama). (a) DDM of the initial two structures; (d) final DDM after a sequence of rigid-body transformations (see text); (e–h) wire-frame superpositions of the same structures depicted by DDMs in (a–d): the black wire shows the unchanging reference conformation of 9aat(A) and the gray wire shows the 1ama structure changing on rigid-body movement (see text). Notation is the same as in Fig. 2 ▶, except that only residues present in the PDB files of both molecules are included in the DDM calculation and these residues are numbered sequentially.