Table 2.

Basal and peak stress plasma corticosterone levels and adrenal weights in C2CR mice

	Control	C2CR
Plasma corticosterone (nm)
Basal	58.3 ± 18.1	63.2 ± 8.1
Stress	257.0 ± 89.4*	254.3 ± 33.6*
Adrenal weight (mg)	0.6 ± 0.04	0.6 ± 0.01

Plasma corticosterone levels were determined in the C2CR and control mice at two states: unstressed (basal) and stressed (after 10 min restraint). Stress was applied using a restraint tube and the blood samples were collected once between 07:00 h and 08:00 h. Stress increased plasma corticosterone levels in both control and C2CR mice, but there was no genotypic difference. Adrenal weights were almost identical in the control and C2CR mice. Data are mean ± SEM; n = 6; *P < 0.01 compared with the respective basal levels.