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. Author manuscript; available in PMC: 2009 Nov 16.
Published in final edited form as: Nat Med. 2002 Oct 7;8(11):1296–1302. doi: 10.1038/nm786

Fig. 2.

Fig. 2

Direct interaction of ANXA1 with ALXR: competitive [125I-Tyr]Ac2-26 and [3H]LXA4 binding. a and b, Human ALXR-transfected HEK293 cells (0.5 × 106) were incubated with [3H]LXA4 (a) or [125I-Tyr]Ac2-26 (b) in the presence of an increasing concentration of unlabeled compounds: LXA4 (◆), Ac2-26 (■), Ac2-12 (△), ANXA1 (○) or scrambled Ac2-6 (□). c and d, Suspension (c) or adherent human PMNs (d) were incubated with [125I-Tyr]Ac2-26 in the presence of increasing concentration of unlabeled compounds: LXA4 (◆), Ac2-26 (■) or SAA (□). Insets in b and c, Scatchard plots of specific [125I-Tyr]Ac2-26 binding. Results represent the mean ± s.e.m. from duplicates of n =3.