Table 1.

Case reports of propylthiouracil-related liver injury in pediatric patients.

Authors, year	Age (years)	Gender	Daily dose (mg)	Duration of PTU	Liver abnormality	Outcome
Moore, 1946 [8]	12	F	300	0.5 months	Liver injury	Recovery
Parker, 1975 [12]	9	F	300	2 months	Portal inflammation cholestasis	Recovery
Reddy, 1979 [14]	10	F	300	1.2 months	Hepatitis	Recovery
Bloch et al., 1985 [21]	12	M	450	2 months	Hepatitis	Recovery
Garty et al., 1985 [22]	12	F	300	1 month	Hepatitis	Recovery
Limaye and Ruffolo, 1987 [24]	6	F	300	4 months	Hepatitis	Recovery
Jonas and Eidson, 1988 [25]	13	F	300	7 months	Massive necrosis	Death
Baker et al., 1989 [26]	9	F	300	3 months	Hepatitis	Recovery
Kirkland, 1990 [29]	9	F	300	4 months	Liver failure	Transplant/Recovery
Levy, 1993 [31]	11	F	300	14 months	Liver failure	Death
Deidiker and deMello, 1996 [41]	13	F	250	4 months	Liver failure	Transplant/Death
Williams et al., 1997 [43]	14	F	450	4 months	Liver failure	Transplant/Recovery
Testa et al., 2003 [35]	17	F	450	6 months	Liver failure	Transplant/Recovery
Sipe et al., 2006 [37]	7	F	300	9 months	Liver failure	Transplant/Recovery