Hamburger,
1985 [57] |
182 |
31 |
17% |
11
Cutaneous |
1
Cutaneous and neutropenia |
1
Cutaneous and rheumatological |
1
Cutaneous and hepatic |
1
Cutaneous and pharyngitis |
4 Neutropenia |
2
Hepatic |
1
Rheumatological |
2 Nausea |
5
Multiple infections without neutropenia |
1
Unspecified |
|
Lippe et al.,
1987 [59] |
63 |
1 |
1.5% |
1
Arthritic reaction |
|
Ward et al.,
1999 [62] |
33 |
8 |
24% |
Rash,
arthralgia, nausea, vomiting |
|
Lazar et al.,
2000 [63] |
28 |
14 |
35% |
2 Major;
agranulocytosis; toxic hepatitis |
12 Minor |
|
Somnuke et al.,
2007 [61] |
32 |
2 |
6% |
ANCA;
nephritis |
Rash,
arthralgia |
|
Glaser and Styne,
2008 [56] |
70 |
11 |
16% |
1 Rash |
2 Rash
and arthralgia |
1
Arthritis with purpura |
1
Arthritis with purpura, hematuria |
3
Elevated liver function tests |
2 Marked
elevated liver function tests |
2
Neutropenia |
|
Ma et al., 2008 [60] |
40 |
8 |
20% |
6
Serious |
48 |
7 |
14.6% |
NA |