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. 2009 Nov 24;4(11):e7988. doi: 10.1371/journal.pone.0007988

Table 1. Summary of tumor types screened by High Resolution Melt Curve Analysis (HRM).

Total cases nā€Š=ā€Š752 (excluding controls) Normal by HRM Confirmed positive for FOXL2 c.402C>G mutation out of HRM positive cases
Ovarian cancer negative controls 14 11 0/3*
Ovarian A-GCT positive controls (including an unreported A-GCT case and the A-GCT cell line, KGN) 13 0 13/13
Bladder Cancer 40 40
Breast Cancer 74 71 0/3*
Carcinoid Cancer 8 8
Cervical Cancer 16 16
Colorectal Cancer 77 75 0/2*
Endometrial Cancer 12 12
Esophageal Cancer 21 21
Gastric Cancer 90 89 0/1*
Head & Neck Cancer 28 26 0/2*
Hepatic (HCC & Cholangiocarcinoma) 14 14
Lung Cancer (All types) 125 123 0/2*
Melanoma 31 31
Ovarian Cancer 32 32
Pancreatic Cancer 4 4
Prostate Cancer 37 37
Renal Cancer 52 51 0/1*
Leiomyosarcoma 15 15
Malignant fibrous histiocytoma-pleomorphic sarcoma 8 8
Rhabdomyosarcoma 2 2
Liposarcoma 4 4
Fibrosarcoma 1 1
Testicular Cancer 19 18 0/1*
Thyroid Cancer 42 42

Sequence data is available for all screen positive samples.

*

Variants seen on HRM screen but not confirmed by sequencing (HRM false positive results).