Table II.

Thermodynamic Parameters Used as Input for the Three-Segment Model of YopM

	(kcal mol−1)
	Constraineda	Distributedb	m (kcal mol−1 M−1)
N-6	−1.68	−1.68	2.4
Interface 6/7	−5.78	−2.42	0
LRRs 7–11	0.95	−2.42	2.84
Interface 11/12	−4.95	−2.1	0
12-β-cap	0.75	−2.1	1.22

^aFree energies based on constraints described in text.

^bFree energies distributed equally between the interfaces and C-terminal segments.