Table 3. Blood Chemistry Analysis.
| Test | WT (n = 3) | HET (n = 3) | KO (n = 4) | p-value** |
| BUN (mg/dL) | 17.67±2.60* | 18.33±1.20 | 37.25±5.73 | 0.01086 |
| Glucose (mg/dL) | 250.6±5.04 | 227.0±11.7 | 143.50±8.81 | 0.000131 |
| Total Protein (g/dL) | 4.200±0.058 | 4.10±0.000 | 4.10±0.252 | NS |
| Albumin (g/dL) | 2.70±0.000 | 2.63±0.067 | 2.60±0.200 | NS |
| Globulin (g/dL) | 1.50±0.580 | 1.47±0.067 | 1.50±0.058 | NS |
| Calcium (mg/dL) | 11.13±0.120 | 10.87±0.120 | 10.18±0.295 | 0.000385 |
| Phosphorus (mg/dL) | 12.60±0.306 | 12.37±0.318 | 12.73±0.544 | NS |
| Sodium (Eq/L) | 143.00±0.577 | 143.67±0.667 | 142.00±6.00 | NS |
| Potassium (mEq/L) | 8.97±0.219 | 8.90±0.252 | 9.90±1.9 | NS |
| Chloride (mEq/L) | 108.67±0.667 | 108.67±1.20 | 112.50±1.50 | 0.02769 |
| Total CO2 (mEq/L) | 21.67±0.333 | 21.33±0.333 | 14.50±3.5 | 0.006227 |
| Osmolality (mOsmo/kg) | 306.23±0.517 | 306.50±1.55 | 304.75±14.2 | NS |
*Values are presented as the average±SEM.
**p-value using student's t-test comparing WT+HET vs. KO; NS-p>0.05.