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Effects of injected PKC on closed-state inactivation of Kv4.3-S (A), Kv4.3-L (B), and Kv4.3-L[T504A] (C). Voltage-clamp protocol is described in Fig. 3 legend. Normalized peak currents, before and after injection of 0.97 ng of PKC, are plotted as a function of P3 pulse duration. Note that PKC had opposite effects on the magnitude of closed-state inactivation in Kv4.3-S and Kv4.3-L. The effects of PKC on Kv4.3-S and Kv4.3-L[T504A] were similar.
