Fig. 8.
Effects of injected PKC on Kv4.3 splice variants. A and B: current recordings for Kv4.3-L during a 0.033-Hz pulse train consisting of 2,000-ms depolarizing pulses between −90 and +50 mV (HP = −90 mV) in control (A) and after injection of PKC (B). Injected PKC (0.97 ng) decreased peak normalized currents at potentials positive to −40 mV in both Kv4.3-S (C) and Kv4.3-L (D). Injected PKC had no significant effects on G/Gmax in both Kv4.3-S (E) and Kv4.3-L (F). Data from two-microelectrode recordings were leakage subtracted.