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. 2009 Sep 16;297(5):1124–1132. doi: 10.1152/ajpcell.00043.2009

Fig. 4.

Fig. 4.

MSTN inhibits IGF-I-mediated myotube hypertrophy through Akt. A: representative photographs of adenovirally infected, GFP-expressing myotubes. B: quantification of mean myotube diameter ± SE expressed as percent GFP control. A minimum of 5 myotubes per condition from 3 to 9 independent experiments were measured. (GFP, n = 104), (G+I, n = 53), (MSTN, n = 113), (M+I, n = 47), (Akt, n = 76), (MSTN+Akt+I, n = 58), (MSTN+Akt = IGF-I, n = 33) *P < 0.001 vs. GFP, #P < 0.05 vs. GFP, ‡P < 0.001 vs. GFP+IGF-I; scale bar, 50 μm (magnification: ×200).