Fig. 7.
DIDS inhibition of unidirectional anion fluxes across Caco-2 monolayers in standard bicarbonate buffer. Open symbols in this figure represent Con monolayers, solid symbols signify A6KD monolayers; circles represent JMS (MS) and squares JSM (SM). A: time course of mucosal DIDS (100 μM) inhibition of [14C]oxalate transport across short-circuited Con monolayers (n = 7) and A6KD (n = 9) monolayers. B: time course for 36Cl− fluxes measured across Con (n = 7) and A6KD (n = 7) Caco-2 monolayers. Current and conductance were not significantly altered by mucosal DIDS. Error bars represent ±1 SE.