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Effect of pertussis toxin (PTX) (100 μg/ml) on muscle contraction induced by PGF2α (10−6 M) and basal levels of PGF2α in intact colon muscle cells. A: PTX reduced the basal MI (*P < 0.01 by ANOVA). B: it also decreased the contraction induced by PGF2α (10−6 M) (**P < 0.01 by ANOVA). C: PTX had no effect on the PGF2α levels. Values are means ± SE of n = 4.
