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. 2009 Sep 17;297(5):G886–G893. doi: 10.1152/ajpgi.00184.2009

Fig. 4.

Fig. 4.

Effects of selective and nonselective (indomethacin) inhibitors on basal MI (A) and on PGF2α levels (B) in cells from normal animals. SC560, a cyclooxygenase (COX)-1 inhibitor (10−5 M), decreased the basal MI (*P < 0.01 by ANOVA) and the levels of PGF2α (#P < 0.01 by ANOVA). In contrast, NS398 (10−5 M), a COX-2 inhibitor, increased the basal MI (**P < 0.01 by ANOVA) and the levels of PGF2α (##P < 0.05 by ANOVA). Indomethacin (10−5 M) lowered the basal MI and the PGF2α levels (&P < 0.01 by ANOVA). Values are means ± SE of n = 4.