TABLE 4.

OR (95% CI) for MetS in association with APOA5 polymorphisms, overall and by category of total fat intake¹²

	APOA5 -1131T > C		SNP, P-value	APOA5 S19W		SNP, P-value
	TT	TC+CC			CC		CG+GG
Overall	1.00	0.87 (0.59–1.29)	0.490	1.00	0.94 (0.62–1.41)	0.749
<31% fat energy3	1.00	0.95 (0.54–1.66)	0.847	1.00	1.00 (0.54–1.84)	0.999
≥31% fat energy	1.00	0.84 (0.49–1.47)	0.546	1.00	0.91 (0.52–1.60)	0.746

¹n = 802, adjusted for age, sex, smoking, alcohol intake, population admixture, and medication use (lipid-lowering, diabetes, and hypertension).

²Participants were classified as having MetS if they had ≥3 of the following conditions: waist circumference ≥102 cm in men or ≥88 cm in women; fasting glucose ≥5.6 mmol/L; elevated blood pressure (SBP ≥ 130 or DBP ≥ 85 mm Hg); high TG (≥1.7 mmol/L); low HDL-C (<1.0 mmol/L in men or <1.3 mmol/L in women).

³Category of total fat intake defined as below or above the population median.