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Expression of IFNs and IL-10. PBS or elastase/LPS mice were inoculated with RV1B and euthanized 1, 4, 7, or 14 days postinoculation (PI) by qPCR and ELISA. A and B: whole lung mRNA and protein levels, respectively, of IFNγ; mRNA levels of IFNα (C), IFNβ (D), IRF-7 (E), and IL-10 (F). N = 3–5, *different from respective sham-infected mice, P ≤ 0.05; †different from elastase/LPS group, P ≤ 0.05, 2-way ANOVA.
