Table 2.
Phospholipid binding of wild-type and mutant peptides at pH 4.0 and 7.4
Peptide | Fluorescence Emission Ratio (415/505 nm), % |
|
---|---|---|
pH 4.0 | pH 7.4 | |
31–40 aa | ||
WT | 100 | 33.7±1.8 |
S32A | 28.2±1.5 | 14.1±0.1 |
25–34 aa | ||
WT | 42.8±1.6 | 0 |
H26A | 0 | 0 |
Values are means ± SE. WT, wild type.