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The AE2 inhibitor DIDS decreases Cl− uptake in type I cells. 36Cl uptake was measured both in the absence and in the presence of DIDS (10−4 M) in terbutaline-treated TI cells. DIDS inhibited Cl− uptake by 25% compared with controls (n = 6 cell isolations, *P < 0.05). Results are expressed as %change from control in pmol Cl−/μg protein (%control) ± SE.
