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. Author manuscript; available in PMC: 2009 Nov 16.
Published in final edited form as: Mucosal Immunol. 2008 Jan;1(1):49–58. doi: 10.1038/mi.2007.5

Figure 4.

Figure 4

HIV-specific CD8 T cells in blood and GI tract. (a) HIV-specific CD8 T-cell responses in blood and gut defined functionally. (b) HIV-specific CD8 T cells in blood and gut defined physically. GI tract and peripheral blood lymphocytes from subjects 1458, 1479, and 1456 were stimulated with overlapping HIV peptides and stained as described in Methods. The responses are shown as the percentage of memory T cells that are HIV-specific (a). Alternatively, tetramer analysis was performed on GI tract and peripheral blood lymphocytes from subjects 1430, 1458, and 1469, and the frequencies of memory CD8 T cells that bind HIV tetramers are shown (b). GI, gastrointestinal.