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. Author manuscript; available in PMC: 2010 Oct 9.
Published in final edited form as: Circ Res. 2009 Sep 10;105(8):764–774. doi: 10.1161/CIRCRESAHA.109.206698

Figure 4.

Figure 4

Ca2+ regulatory proteins in hCPCs. A-D, Expression at the mRNA (A) and protein (B-D) levels of the components of the ER that are implicated in Ca2+ homeostasis. Myocytes were used as positive control for RyRs. Human heart (hHeart) was used as positive control. Scale bars: 20 μm. E, Repetitive Ca2+ oscillations in hCPCs in the presence of IP3R agonist. F-H, Ca2+ oscillations in hCPCs at baseline (Tyrode) and in the presence of activation (F) and inhibition (G and H) of IP3R function. Xestopsongin-C, XeC. I-N, Ca2+ in hCPCs in the presence of modulators of SERCA (I and J) and RyRs (K-N). *P<0.05 vs. Tyrode.