Figure 5.
A structure of the human AGT/DNA complex. a A monomer AGT protein binds at the junction of the two DNA fragments, and recognizes a terminal overhanging thymine. This base is inserted into the active site pocket only partially rather than forming a base pair with the adenine overhang from the adjacent DNA. b Cartoon presentation of the AGT protein binding the junction of two duplex DNA. The finger residue, Arg128 that intercalates inside the duplex and fills the gap left by base flipping, is shown.