Figure 7.
Combination of Bauer Alkylamides 10 and 11 at the concentrations found in fraction 3E (Table 2). The bars represent PGE2 levels after induction with 1 μg/ml LPS and treatment with an Echinacea fraction (n = 3). All treatments + LPS were compared to media + DMSO + LPS control that was set at 100 % PGE2 production (4.4 ng/ml). Treatments were also performed without LPS induction showing significant reduction of PGE2 with fraction 3E (p = 0.0275). The treatments without LPS were compared to the media + DMSO control set at 100 % PGE2 production (0.2 ng/ml). Quercetin was used as the positive control. * and ** are representative of p<0.05 and p<0.001. Each bar represents % of control ± standard error.