Figure 9.
Results of immunostaining for phosphorylated Smad2 (pSmad2) (A, C, and E) and TSP1 (B, D, and F) in primary colorectal cancers. A-B. Nuclear pSmad2 is present in most of the epithelial cells and TSP1 expression is present. C-D. Heterogeneity of expression of pSmad2 and TSP1 is present in this tumor. Co-localization of pSmad2 and TSP1 can be appreciated. E-F. No expression of pSmad2 or TSP1 is present. (Magnification: 100X).