Table 6.
Model-estimated time point probability of immune recovery by the type of cancer adjuvant therapy
Time point (month) |
Chemotherapy Probability |
Radiotherapy Probability |
Chemo+ Radiotherapy Probability |
p | |
---|---|---|---|---|---|
CD4 | 2 | 0.45 | 0.65 | 0.46 | .39 |
6 | 0.45 | 0.60 | 0.58 | .59 | |
12 | 0.18A | 0.77B | 0.62B | .002 | |
CD56 | Combined | 0.66 | 0.70 | 0.73 | .77 |
CD8 | Combined | 0.63 | 0.68 | 0.59 | .66 |
IFN-r | 2 | 0.33 | 0.21 | 0.51 | .17 |
6 | 0.25 | 0.53 | 0.43 | .27 | |
12 | 0.23 | 0.31 | 0.21 | .82 | |
IL-1α | Combined | 0.56 | 0.25 | 0.33 | .10 |
IL-2 | Combined | 0.11A | 0.73B | 0.29A | .004 |
IL-4 | Combined | 0.41A | 0.09B | 0.26A | .002 |
IL-6 | Combined | 0.67 | 0.53 | 0.56 | .56 |
NK (MV) | Combined | 0.27 | 0.37 | 0.38 | .65 |
LAK (MV) | 2 | 0.33 | 0.37 | 0.24 | .54 |
6 | 0.49 | 0.45 | 0.45 | .66 | |
12 | 0.33A | 0.50 | 0.58B | .05 | |
LP (MV) | Combined | 0.29 | 0.37 | 0.38 | .82 |
Notes. Pairs of treatment group with different letters (e.g., A and B, A and C, B and C) are significantly different at p < .05.
Combined: Collapsed over types of cancer adjuvant therapy, as interaction with time was not statistically significant.
NK: natural killer cell activity. LAK: lymphokine-activated killer cell activity. LP: lymphocyte proliferation. MV: Multivariate model tested.