Fig. 1. DIM up-regulates BRCA1 expression.
A. Subconfluent proliferating cells were incubated with 10 µM DIM (or DMSO) for 24 hr and Western blotted for BRCA1 and α-actin (loading control). B–D. Cells were treated with DIM for the indicated times using the indicated concentrations and harvested for Western blotting for BRCA1, BRCA2, and α-actin.