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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: J Pain. 2009 Apr 19;10(8):836–843. doi: 10.1016/j.jpain.2009.02.003

Figure 3.

Figure 3

Leptin replacement restored the antinociceptive effect of pontine reticular formation neostigmine in obese mice. Graph shows %MPE values averaged over the course of 2 h following microinjection of saline or neostigmine for obese mice, B6 mice, and obese mice that received leptin replacement. Asterisks indicate a significant difference (P<0.05) between response to neostigmine and saline.