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. 2009 Jul 8;297(5):R1215–R1227. doi: 10.1152/ajpregu.90800.2008

Fig. 2.

Fig. 2.

Observed distribution (top) and analytical reconstruction (middle) of the tripartite relationship among calculated pulsatile LH secretion rates, serum ganirelix (GRX) concentrations, and age in 24 healthy men. A 3-parameter exponential model was used to represent the GRX-LH inhibitory interface. Estimated inhibitory functions projected to ages 20 and 80 yr and age-dependent linear increase in inhibitory sensitivity (bottom).