Table 1.
Summary statistics for age effects
| Dependent Variable | Slope | SE of Slope | t Value | df | One-Sided P Value* |
|---|---|---|---|---|---|
| LH → Te feedforward | |||||
| LH ED50, IU/l | −0.0071 | 0.0120 | −0.62 | 22 | 0.270 |
| LH efficacy, ng·dl−1·min−1 | −0.0440 | 0.025 | −1.75 | 22 | 0.047 |
| Testis sensitivity, slope units | 0.0055 | 0.0130 | 0.43 | 22 | 0.66 |
| Basal Te secretion, ng·dl−1·min−1 | 0.0024 | 0.0020 | 1.44 | 22 | 0.92 |
| GnRH and Te → LH | |||||
| Basal LH secretion, IU·l−1·min−1 | −0.0001 | 0.0000 | −0.20 | 22 | 0.42 |
| GnRH efficacy, IU·l−1·min−1 | −0.0227 | 0.010 | −2.26 | 22 | 0.017 |
| Te feedback on GnRH/LH, slope units | −0.0006 | 0.0002 | −2.41 | 22 | 0.012 |
Data are based on regression of the indicated dependent variable on age (n = 24 subjects). LH, luteinizing hormone; df, degrees of freedom; Te, testosterone; GnRH, gonadotropin-releasing hormone.
*
Against null hypothesis that age does not decrease the indicated dose-response parameter.