Table 2.
Sample parameter estimates
| Parameter | Mean | SE |
|---|---|---|
| GnRH drive and free Te feedback on LH secretion | ||
| Basal LH secretion, IU·l−1·min−1 | 0.0671 | 0.0131 |
| η0, unitless | 0.0557 | 0.6429 |
| η1, unitless | 0.5331 | 0.1712 |
| GnRH potency, unitless | 1.6153 | 0.1119 |
| GnRH efficacy, IU·l−1·min−1 | 12.5336 | 1.7546 |
| Te feedback, exponential coefficient | 0.0680 | 0.0041 |
| β1, unitless | 11.6675 | 0.9604 |
| β2, unitless | 0.0066 | 0.0037 |
| β3, unitless | 0.2516 | 0.0112 |
| SD of residuals | 0.0608 | 0.0047 |
| SD of random effects | 15.6919 | 3.4938 |
| LH-driven Te secretion | ||
| t1/2, min | ||
| Fast free Te | 0.9224 | 0.0580 |
| Slow free Te | 4.6903 | 0.4363 |
| Total Te | 53.2500 | 3.0242 |
| Basal Te secretion, ng·dl−1·min−1 | 0.0330 | 0.0274 |
| LH potency, IU/l | 1.1314 | 0.1112 |
| Sensitivity, slope units | 2.0312 | 0.2013 |
| Efficacy, ng·dl−1·min−1 | 3.8440 | 0.4191 |
| SD of residuals | 1.6487 | 0.2767 |
| SD of random effects | 52.8094 | 5.7098 |
Potency = ln (−potency coefficient); t1/2, half-life. For sample (n = 24) and individual-parameter correlations, see supplemental information in the online version of this article.