Fig. 2.

Representative histological images of multilocular and unilocular adipocytes. Left: A section of adipose tissue from the perirenal depot in a chronically sleep-restricted rat illustrative of heterogeneity of the morphology and prevalence of multilocular adipocytes in some regions. Multilocular regions are clusters of notably small yet relatively uniformly sized lipid droplets encased within a single membrane. Right: section of adipose tissue from the perirenal depot of an ambulation-control rat showing a unilocular phenotype with a comparatively homogeneous cell size. Stained with hematoxylin and eosin. Bar = 50 μm.