Table 2.

Rat weight, adiposity, and UCP1 protein levels at death

	rAAV-Control	rAAV-Leptin Antagonist
Rat weight, g	404±10	449±13*
PWAT, g	1.46±0.11	1.94±0.07†
RTWAT, g	5.57±0.69	9.04±0.51†
EWAT, g	7.51±0.81	10.49±0.19†
Adiposity, g	14.54±1.57	21.47±0.58†
UCP1 per BAT	100±20.4	102±19.6

Data were derived from rats given the higher dose of leptin antagonist and represent means ± SE of 5 rats/group. Adiposity represents the sum of perirenal (PWAT), epididymal (EWAT), and retroperitoneal (RTWAT) white adipose tissue. Uncoupling protein 1 (UCP1) levels in rAAV-Control rats were set to 100, with SE adjusted proportionally; BAT, brown adipose tissue.

^*P < 0.05,

^†P < 0.01 for difference from corresponding rAAV-Control by t-test.