Table I.
Females | Normal (n = 6) | Early-treated PA (n = 5) | Late-treated PA (n = 3) |
---|---|---|---|
Age (years)* | 21.6 ± 0.7 | 23.3 ± 0.8 | 19.2 ± 1.1b |
BMI (kg/m2)* | 43.0 ± 2.1 | 34.7 ± 2.3 | 38.4 ± 2.9 |
Serum FSH (ng/ml)** | 3.2 (2.3, 4.3) | 2.4 (1.6, 3.5) | 2.4 (1.5, 3.6) |
Serum bioactive LH (ng/ml)** | 0.3 (0.2, 0.6) | 0.3 (0.2, 0.5) | 0.3 (0.1, 0.6) |
Serum E2 (nmol/l)** | 0.72 (0.39, 1.35) | 0.14 (0.07, 0.27)c | 0.10 (0.04, 0.26)c |
Serum progesterone (nmol/l)** | 0.64 (0.32, 0.95) | 0.32 (0.32, 0.64) | 0.32 (0.32, 0.64) |
Serum 17OHP4 (nmol/l)** | 0.30 (0.30, 0.91) | 0.61 (0.30, 1.21) | 0.61 (0.30, 2.42) |
Serum A4 (nmol/l)* | 0.69 ± 0.11 | 0.99 ± 0.12 | 1.16 ± 0.15 |
Serum testosterone (nmol/l)* | 0.68 ± 0.14 | 0.91 ± 0.15 | 0.85 ± 0.19 |
Serum DHT (nmol/l)* | 0.51 ± 0.10 | 0.45 ± 0.11 | 0.56 ± 0.14 |
17OHP4: 17-hydroxyprogesterone, DHT: dihydrotestosterone, A4: androstenedione, E2: estradiol, early-treated PA: starting PA on days 40–44 postconception (total gestation, 165 days), late treated PA: starting PA on days 100–115 postconception.
aMean ± SE*, back-transformed log10 mean (95% CI)**.
bP < 0.025 versus early-treated PA females.
cP < 0.01 versus normal females.