Fig. 3.
Intact diaphragm force-frequency curves. Intact muscle force generation was significantly lower at stimulation frequencies from 1 to 80 Hz for diaphragms from CLP-treated animals (●) than for control animals (□) (P < 0.001). Diaphragms from CLP animals given CI III (▵) generated forces significantly higher than diaphragms from CLP animals for frequencies from 1 to 80 Hz (P < 0.01). Force generation for muscles taken from CLP animals given zVAD-fmk (▼) was also greater than for CLP animals (frequencies 1–80 Hz, P < 0.01). *Significant statistical difference between CLP and the other groups, P < 0.05.