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Single-skinned fiber force-pCa curves. Single skinned fiber force generation for diaphragm muscle fibers from CLP animals (●) was significantly reduced compared with the force generated by single-diaphragm fibers from control animals (□) (P < 0.001). Forces generated by single skinned fibers from either CLP plus CI III (△) or CLP plus zVAD-fmk groups (▼) were significantly higher than the force generated by fibers from the CLP group (P < 0.001).
