Table 2.
Glucocorticoid-regulated genes distinctive to CEM cells destined for apoptosis
| A Induced genes | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Probe i.d. | GenBank Acc. No. | Potential GREsa |
TF sites ± 100 ntb |
Namec | |||||
| Palindrome | 1/2 GRE | AP-1 | c/EBP | NFκB | Oct-1 | CREB | |||
| 37294_at | X61123 | 1 | 1 | 2 | BTG1 | ||||
| 41592_at | AB000734 | SOCS-1 | |||||||
| 36227_at, 1370_at | AF043129, M29696 | 1 | 1 | 2 | 2 | IL7R | |||
| 36591_at, 330_s_at | X06956, HG2259-HT2348 | TUBA1 | |||||||
| 36231_at | AC002073 | clone DJ51 5N1 | |||||||
| 37544_at | X64318 | E4BP4 | |||||||
| 41872_at | AF073308 | 1 | 1 | 1 | DFNA5 | ||||
| 35985_at | AB023137 | paralemmin 2 | |||||||
| 38717_at | AL050159 | 1 | 1 | 1 | 1 | DKFZp586A0522 | |||
| 32112_s_at, 32113_at | AI800499, U83115 | AIM1 | |||||||
| 32168_s_at | U85267 | DSCR1 | |||||||
| 995_g_at | X58288 | PTPRM | |||||||
| 41524_at, 656_at | L08488 | 1 | 1 | 1 | INPP1 | ||||
| 1102_s_at, 36690_at | M10901 | GRα | |||||||
| 38378_at | M37033 | MOX44 | |||||||
| 1427_g_at | D89077 | 1 | 1 | 2 | 1 | SLAP | |||
| 32542_at | AF063002 | SLIM1 | |||||||
| 735_s_at | HG2167-HT2237 | 2 | 4 | 1 | 2 | 2 | PKHt31 | ||
| 1461_at | M69043 | MAD-3, NFKBI | |||||||
| 31508_at | S73591 | 1 | 1 | 2 | 3 | 2 | VDUP1 | ||
| 32215_i_at, 32216_r_at | AB020685 | KIAA0878 | |||||||
| 31611_s_at | AF032457 | BIMEL | |||||||
| 35854_at | L14269 | 1 | 3 | 1 | SLC18A2 | ||||
| 35164_at | AF084481 | DFNA6 | |||||||
| 37112_at | AB002384 | DIFF40 | |||||||
| 38866_at | Z82206 | 2 | 1 | 11 | GRAP2 | ||||
| 32526_at | AA149644 | JAM3 | |||||||
| 1717_s_at | U45878 | 1 | 1 | 1 | 5 | BIRC3 | |||
| 36634_at | U72649 | 1 | 1 | 4 | 1 | 3 | BTG2 | ||
| 38799_at | AF068706 | AP1G2 | |||||||
| 37645_at | Z22576 | 1 | 2 | 1 | 2 | CD69 | |||
| 1814_at, 1815_g_at | D50683 | TGFBR2 | |||||||
| 390_at | X85740 | CMKBR4 | |||||||
| 38671_at | AB014520 | 1 | 1 | KIAA0620 | |||||
| 38661_at | X75315 | RNPC1 | |||||||
| 35917_at | W26631 | MAP1A | |||||||
| 33804_at | U43522 | 1 | 2 | 4 | 5 | PTK2B | |||
| 35763_at | AB011112 | 1 | 4 | 1 | KIAA0540 | ||||
| 32227_at | X17042 | 2 | 2 | 3 | 3 | 1 | PRG1 | ||
| B Repressed genes | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Probe i.d. | GenBank Acc. No. | Potential GREs |
TF sites ± 100 nt |
Name | |||||
| Palindrome | 1/2 GRE | AP-1 | c/EBP | NFκB | Oct-1 | CREB | |||
| 1077_at | M29474 | RAG1 | |||||||
| 37393_at | L19314 | HRY | |||||||
| 40455_at | AB020637 | 1 | 1 | 4 | KIAA0830 | ||||
| 1973_s_at, 37724_at | V00568 | 1 | 1 | 3 | 1 | c-myc | |||
| 40692_at | M99439 | 2 | 2 | 1 | 1 | TLE4 | |||
| 34805_at | AA195301 | 1 | 1 | 3 | 1 | 1 | 2 | MGC2574 | |
| 34517_at | X66435 | HMGCS1 | |||||||
| 38277_at | M29550 | 1 | 7 | 2 | 1 | PPP3CA | |||
| 38505_at | AL050151 | DKFZp586J0720 | |||||||
| 39235_at | AC003038 | 1 | 1 | 1 | 2 | 2 | 1 | DNA from cosmidR30923 | |
| 32118_at | AF076838 | 1 | 1 | 2 | RAD17 | ||||
| 34341_at | U00238 | 1 | 2 | 2 | GPAT | ||||
| 41861_at | AL050019 | DKFZp564C186 | |||||||
| 2061_at | L12002 | ITGA4 | |||||||
| 31838_at | U79274 | 1 | 3 | 1 | 1 | HSU79274 | |||
| 34998_at | AF059531 | PRMT3 | |||||||
| 41259_at | AI553745 | HSPC111 | |||||||
| 40729_s_at | Y14768 | LTB | |||||||
| 40020_at | AB011536 | CELSR3 | |||||||
| 35246_at | U18934 | 1 | 1 | TYRO3 | |||||
| 40982_at | AA926957 | 1 | 2 | FLJ10534 | |||||
a
Evaluations of GRE quality were based on criteria in Beato et al. [26].
b
Selected sites for transcription factors shown within 100 nucleotides of a GRE.
c
See GenBank or Celera databases for aliases.