Fig. 1. Astrocytes derived from adult and newborn hippocampus and spinal cord expressed different sets of genes.
(a) Sample correlation coefficient (cc) plots of signal intensity (representing gene expression levels) obtained by using MAS4.1 software (Affymetrix); Note that replicates (NBH1 vs. NBH2, ADS1 vs. ADS2) had similar gene expression profiles (high cc values), whereas samples from different tissues (NBH vs. ADS, NBH vs. ASF) had distinct gene expression profiles (low cc values); (b) A modified Venn Diagram showing numbers of genes that are unique or common among these astrocytes derived from different tissues; Among 5,190 genes that are “Present” in at least one astrocyte sample, 3,394 (65.4%) genes were shared by all four types of astrocytes, 914 (17.6%) genes were shared by 3 types of astrocytes, 537 (10.3%) genes were shared by two types of astrocytes, and 527 (10.2%) genes were only “Present” in one type of astrocyte; (c) Among the 3,394 common genes shared by the astrocytes, 3,231 genes are also shared with ASF.