Table 1.
Effects of vagotomy on passive, active, and synaptic properties
| P | n | Control | n | Vagotomy | |
|---|---|---|---|---|---|
| Rm, MΩ | 0.9 | 66 | 354 (268–490)* | 43 | 373 (261–470)* |
| Cm, pF | 0.7 | 66 | 21 (18–25)* | 43 | 20 (18–25)* |
| Vm, mV | 0.4 | 66 | −64 (−69 to −59)* | 43 | −62 (−67 to −55)* |
| Excitability, No. of spikes | 0.9 | 66 | 33 ± 2§ | 43 | 32 ± 2§ |
| Latency, ms | 0.8 | 66 | 3.9 ± 0.2§ | 43 | 4 ± 0.2§ |
| Jitter, μs | 0.6 | 66 | 83 (63–116)* | 43 | 91 (71–124)* |
| spEPSC frequency, Hz | 1.0 | 66 | 4.7 (3 to 9)* | 43 | 5.4 (2 to 13)* |
| spEPSC amplitude, pA | 0.9 | 66 | −28 (−22 to −40)* | 43 | −30 (−25 to −36)* |
| mEPSC frequency, Hz | 0.7 | 8 | 8 ± 2§ | 4 | 7 ± 3§ |
| mEPSC amplitude, pA | 0.8 | 8 | −34 ± 4§ | 4 | −36 ± 8§ |
| evEPSC decay time, ms | 0.5 | 12 | 3.1 ± 0.2§ | 12 | 2.9 ± 0.2§ |
Passive, active and synaptic properties in the nucleus tractus solitarius are unchanged following vagotomy. Rm, membrane resistance; Cm, membrane capacitance; Vm, membrane potential; spEPSC, spontaneous excitatory postsynaptic current (EPSC); mEPSC, miniature EPSC recorded in the presence of TTX.
median (25–75% confidence interval).
mean ± SE. n, sample size.