Table 5.

Analysis of hot spot predictions for each amino acid type

Mutated amino acid	Nmut	TP	TN	FP	FN	P	R	F1	A
Arg	33	5	16	10	2	0.33	0.71	0.45	0.64
Asn	22	3	15	1	3	0.75	0.50	0.60	0.82
Asp	29	7	15	5	2	0.58	0.78	0.67	0.76
Cys	1	0	1	0	0	NA	NA	NA	1.00
Gln	21	1	17	2	1	0.33	0.50	0.40	0.86
Glu	31	1	22	4	4	0.20	0.20	0.20	0.74
His	13	1	11	1	0	0.50	1.00	0.67	0.92
Ile	15	0	11	0	4	NA	0.00	NA	0.73
Leu	10	0	9	0	1	NA	0.00	0.00	0.90
Lys	32	10	20	1	1	0.91	0.91	0.91	0.94
Met	2	0	1	1	0	0.00	NA	NA	0.50
Phe	11	1	8	1	1	0.50	0.50	0.50	0.82
Ser	28	1	22	5	0	0.17	1.00	0.29	0.82
Thr	24	0	21	2	1	0.00	0.00	0.00	0.88
Trp	23	5	13	1	4	0.83	0.56	0.67	0.78
Tyr	44	17	17	7	3	0.71	0.85	0.77	0.77
Val	10	1	7	1	1	0.50	0.50	0.50	0.80
All	349	53	226	42	28	0.56	0.65	0.60	0.80

N_mut: number of mutations, TP: true positives, TN: true negatives, FP: false positives, FN = false negatives; P: precision, R: recall, F1: F1 score, A: accuracy = .