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SIV replication in macaque TCBs obtained from SIV-infected animals and cultured with 0 (solid triangle), 9.5 (solid square) or 18.7 (hollow diamond) μM WR1065 for 17 days. SIV p27 values are shown for days 7, 10, 14 and 17 of culture for TCBs from macaques: (A) 612 (0.10 × 106 copies SIV/ml and 376 CD4 cells/ml); (B) 642 (0.03 × 106 copies SIV/ml and 635 CD4 cells/ml); and (C) 674 (6.40 × 106 copies of SIV/ml and 547 CD4 cells/ml).
