Table 2.
WR1065 (μM) | % Cells in S Phase | % Cells in G2/M Phase | % of Cells in G0/G1 Phase |
0 | 5.3 ± 1.6 | 1.3 ± 0.6 | 93.8 ± 2.2 |
9.5 | 6.2 ± 2.6 | 1.3 ± 0.7 | 92.5 ± 3.2 |
18.7 | 8.3 ± 2.5 | 1.5 ± 0.5 | 90.5 ± 2.6 |
a Fresh human TCBs were infected with HIV-1 for 2 hr before incubation for 72 hr with WR1065. Values shown are mean ± range (n = 2). Cell viability, as determined by Trypan blue exclusion was 84.4-87.4% (mean ± range, n = 2).