Fig. 3.

S-OIV–specific CD4⁺ and CD8⁺ T cells appear to have an effector memory phenotype. PBMC from two representative normal donors were stimulated with either pools of (A) CD4⁺ or (B) CD8⁺ T-cell epitopes conserved in S-OIV sequences. The cells were gated for IFN-γ production and presence of the surface markers CD4 and CD8, respectively. Signal intensities of the gated cells for memory phenotypic markers CD45RA, CD62L, and CCR7 are shown.