Table 1.
Variable | Total group (n = 62) |
Regular nicotine cigarette (n = 46) |
De-nicotinized cigarette (n = 16) |
p-value (Nic vs De-Nic groups) |
---|---|---|---|---|
Age | 40.5 (± 1.5) | 41.6 (± 1.7) | 37.3 (± 3.4) | NS |
Percent female | 32.3% | 34.8% | 25.0% | NS |
Cigs/day | 24.2 (± 0.9) | 24.9 (± 1.0) | 22.3 (± 1.6) | NS |
Years of smoking | 22.5 (± 1.5) | 23.5 (± 1.7) | 19.8 (± 3.3) | NS |
Education (yrs) | 13.8 (± 0.2) | 13.8 (± 0.3) | 13.9 (± 0.3) | NS |
FTND | 6.4 (± 0.2) | 6.4 (± 0.3) | 6.4 (± 0.4) | NS |
HAM-D | 1.8 (± 0.3) | 1.5 (± 0.3) | 2.4 (± 0.6) | NS |
HAM-A | 2.0 (± 0.3) | 1.7 (± 0.3) | 2.6 (± 0.8) | NS |
CO level (p.p.m.) | 17.0 (± 1.1) | 17.5 (± 1.5) | 15.3 (± 1.7) | NS |
% Change in UTS (craving) with smoking | −74.9 (± 3.1) | −76.0 (± 3.5) | −71.8 (± 6.9) | NS |
% Change in STAI with smoking | −25.0 (± 15.0) | −26.1 (± 19.5) | −21.7 (± 16.3) | NS |
% Change in Mood with smoking | 7.6 (± 5.4) | 15.2 (± 6.0) | −0.5 (± 4.4) | 0.04 |
Values are stated as mean ( ± SEM); p-values are for unpaired Student’s t-tests between the groups that smoked either a regular nicotine or a denicotinized cigarette. Cig, cigarette; CO, exhaled carbon monoxide; De-Nic, denicotinized; FTND, Fagerström Test for Nicotine Dependence; HAM-A, Hamilton Anxiety Rating Scale; HAM-D, Hamilton Depression Rating Scale; Mood, mood analog rating scale score; Nic, nicotine; NS, nonsignificant; p.p.m., parts per million; STAI, Spielberger State-Trait Anxiety Index state anxiety questions total score; UTS, Urge to Smoke Scale; yrs, years.