Table 1.
Demographics data and admixture rates of our sample
| Ancestry-validated European-Americans (n=3119) | Ancestry-validated African-Americans (n=751) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Size (n) |
Male (%) |
Mean Age (years) |
European ancestry ≥90%a (%) |
Admixture (%) |
P valueb | Size (n) |
Male (%) |
Mean Age (years) |
African ancestry ≥90%a (%) |
Admixture (%) |
P valueb | |
| West Africans | 78 | 38.5 | 98.7 | 0.61±1.71 | ||||||||
| Healthy Controls | 811 | 45.9 | 29.7±11.8 | 96.4 | 1.79±3.94 | 135 | 39.1 | 33.9±12.1 | 91.1 | 3.50±7.90 | ||
| Substance Dependence | 1527 | 67.1 | 41.5±9.9 | 97.8 | 1.38±2.99 | 0.009 | 397 | 65.5 | 39.2±8.1 | 89.7 | 4.27±8.56 | 0.355 |
| Alcohol Dependence | 1450 | 67.0 | 42.0±9.8 | 97.9 | 1.37±2.98 | 0.008 | 330 | 66.7 | 40.7±8.1 | 90.0 | 4.17±8.27 | 0.418 |
| Cocaine Dependence | 259 | 69.9 | 36.9±7.9 | 97.3 | 1.62±4.00 | 0.534 | 200 | 66.5 | 38.7±8.1 | 90.0 | 4.16±8.98 | 0.489 |
| Opioid Dependence | 123 | 57.7 | 37.5±9.2 | 97.6 | 1.39±2.59 | 0.269 | 72 | 58.3 | 41.5±8.6 | 87.5 | 4.58±9.43 | 0.384 |
| Social Phobia | 122 | 45.2 | 39.4±14.2 | 92.6 | 2.23±4.64 | 0.326 | 6 | 50.0 | 36.5±12.8 | 83.3 | 5.22±8.28 | 0.604 |
| Affective Disorders | 363 | 44.9 | 39.8±14.2 | 93.7 | 2.41±5.58 | 0.057 | 37 | 56.8 | 41.4±7.9 | 94.6 | 3.15±5.20 | 0.799 |
| Schizophrenia | 296 | 20.9 | 40.4±11.6 | 96.3 | 1.73±3.60 | 0.814 | 98 | 18.4 | 41.5±11.9 | 82.7 | 7.26±1.35 | 0.015 |
Admixture rates in European-Americans (or African-Americans) represent the African (or European) ancestry proportions in those subjects.
1
The percentages of subjects with European (or African) ancestry proportions ≥90%.
b
α=0.010.