Figure 1. CYP2C8 gene structure and coding region polymorphisms.
The CYP2C8 gene, located on chromosome 10q24, spans 31 kb and consists of nine exons. Coding region polymorphisms are shown in the figure. Gray text signifies synonymous polymorphisms, while the black text signifies nonsynonymous polymorphism.
*Alleles coding for documented or predicted reduced enzyme activity.
Figure reproduced from [115].