Figure 1.
Muscarinic receptor activation elicits LFOs at α frequencies in slices of the cat LGN and VB that require intact GJ-mediated communication. A, LGN extracellular field recording in vitro exhibiting α oscillations after 50 μm Cch application. The corresponding spectrogram is shown below (a.u., arbitrary units). The underlined section is further expanded below. The autocorrelation functions and power spectra pertaining to the Control, Cch, and Wash scenarios are shown on the right. B, Cch-induced LFOs are abolished by the M1/M3 receptor antagonist Pzp. The corresponding autocorrelation functions are shown on the right. C, Spectrogram showing a reversible disruption of Cch-induced α activity by the GJ-blocker 18β-GA. Raw traces are shown below as indicated.